What Does Notox Mean in Skincare?

What is “Notox”?

When you hear about “notox” in the skincare and beauty industry, it is referring to products that are made with all-natural ingredients, promoting a non-toxic lifestyle. While some products advertise they are made “all-natural,” the ingredients in such products may still cause adverse reactions and harsh side effects, such as dry skin and irritation.

At Depology, that is the last of our intentions. Designed with unique and innovative “notox” formulas that are intended for those of all skin types and conditions, your only concern is seeing desired results almost instantly. When we talk about “all-natural,” we intend to keep our word.

All-Natural Notox serum by depology

Skincare can be overwhelming, especially if you are new to the game. Thankfully, we’ve provided some of our core products below, as well as common skincare ingredients that work to promote healthy, glowing skin as well as diminish aging signs.

There’s something out there for everyone, no matter your skin type or concern. Chances are, something is brewing in one of our laboratories around the world that is specifically crafted just for you.



One of our most popular and trending items. Matrixyl 3000 serum is formulated specifically to work alongside our micro dart patches or at-home microneedling treatment. In general, this well-rounded serum formula not only keeps you looking younger but promotes healthy and hydrated skin.

The core ingredient, Matrixyl 3000, is a synthetic peptide that is heavily used to ensure the skin cells are constantly well-taken care of. Working hard alongside other natural ingredients such as hyaluronic acid and glycerin, your skin will be thanking you daily for the application of this formula. It’s advised to use this serum twice a day, both in the morning and right before bed.

For a more in-depth look at how our Matrixyl 3000 formula accomplishes such feats, you can begin your journey here.



This Peptide Complex 10% Serum serum is formulated to halt aging signs in their tracks. Facial movements and expression lines are primary causes of aging signs as we get older, as well as the loss of elasticity in the skin over time. To combat this, Argireline™ works to prevent the movement of muscles that lead to wrinkle formation and other common aging signs.

On top of its ability to work against the natural aging process, Argireline™ is used to promote healthy hydration and retention of moisture in the skin. Our previously mentioned Matrixyl 3000 serum can be applied alongside this powerful formula, as well as our at-home microneedling treatment, which our formulas are well-intentioned to collaborate with.

Argireline™ itself is an industry-favorite peptide that mimics the effects of injectable treatments but without dreadful office visits. If we learned anything from the pandemic, it’s that we can accomplish both our work and our skincare routines from the comfort of our own homes. This formula also features other notable ingredients, such as hyaluronic acid and birch juice, which aid in reducing inflammation and producing plumper, healthier skin, as well as several other benefits.


Another formula that has attracted users of various backgrounds is our Antioxidant Radiance Serum. Recommended to be used both in the morning and evening, these multi-tasking antioxidants in this formula strive to promote firm and brightening skin. Every time we step outside our homes, our skin is exposed to several damaging pollutants and free radicals, which can produce harmful effects as well as speed up the aging process.

This is where our Power C formula becomes relevant to the end goal: achieving firmness in the skin so that a plumper, brighter appearance makes it seem as if your skin was never in harm’s way, to begin with. If that wasn’t enough protection, you can even utilize this serum as extra UV protection alongside your preferred sunscreen, preventing hyperpigmentation.

Powerful ingredients that work together in this formula include Vitamin C, a well-known antioxidant to promote healthy skin. The formula also utilizes goji berry extract, ferulic acid, and ergothioneine, which is an antioxidant that occurs naturally in the body as amino acid, further assisting with free radical damage.



This high-performance treatment serum best suits those with sensitive and irritative skin, but can still be beneficial for all potential skincare users. Formulated with notox ingredients such as cica (Centella Asiatica) blend, multi molecular HA, green ferment complex and vitamin E these ingredients multi-task with the ultimate goal of calming and nourishing the skin while simultaneously preventing free radicals and environmental stresses from causing further damage.

The core ingredient in this formula, cica, has several functions. It improves skin elasticity and firmness, promotes hydration and moisturization, and reduces inflammation. The remaining supporting ingredients in the base formula all serve similar functions, bouncing off of one another to produce desired results after a single use. It is recommended to be applied twice a day, in the morning and evening.

Our Dark Spot Correcting Serum has produced rave reviews for its ability to provide desired results almost instantly for those of varying skin types, particularly those with pigmentation spots. This exquisite formula combination is derived from niacinamide, arbutin, tranexamic acid, and green tea extract, the N.A.T. trio coming together to display its powerful effects when it comes to combatting dark spots, often caused by excess sunlight exposure.

Aside from the trio that primarily focuses on brightening the skin and lessening dark spots, the addition of green tea in this formula contains anti-inflammatory properties that operate as a bonus in reducing skin irritation, swelling, and redness. It can even be used to treat and soothe minor cuts and sunburn.

When shopping for products, a label that describes its formula as “small batch” often offers superior quality compared to other formulas and the freshest, most natural ingredients. These formulas are typically derived from scratch, made specifically with your health in mind from development to consumption.

While these products may end up costing more than general drugstore products, it’s hard to put a price on your skin’s health. You should always strive to avoid unnecessary “fillers,” such as excess water in a formula. Fillers generally cause products to have less shelf life rather than lasting over long periods.


Conclusion : no-tox skincare

As you can see, there’s no reason for your skin to ever be exposed to ingredients that aren’t in the “notox” category. That ageless glow should be achieved without potentially harming your skin further. Our skin does so much good for us and keeps us healthy in a variety of ways, so we should treat it with the same respect and only the highest-quality ingredients in return.

If you’re still curious about which ingredients are a must for promoting healthy and ageless skin, this guide provides several helpful tips that your skin may be thanking you for later.