What Does Matrixyl Do?

Have you ever tried to read and decode the ingredient list on the back of your favourite anti aging skincare product? If you have, you've most likely been perplexed by what these substances are and what they do for your skin and complexion.

Today, we deep-dive into the hot-topic ingredient Matrixyl; we're going to talk about what Matrixyl 3000 does and the advantages it could bring to your skin today.​

Whilst there is a plethora of anti aging skincare ingredients we could discuss, we've chosen Matrixyl 3000 because it is the dominant ingredient in our popular collagen-boosting serum formula. ​

So what does Matrixyl 3000 do for the skin?​ It is a potent ingredient that hydrates the skin while also combating visible signs of ageing and reducing the appearance of fine lines and wrinkles. All forms of Matrixyl are derived from Methionine Sulfone and Lysine. These peptides are also Lipopeptides, which occurs when Amino Acids are mixed with Fatty Acids. Amino acids are a known superfood for collagen stimulation and production in the skin.​

This serum formulation is one of our most game-changing skincare products yet, as it will help you achieve the softest, smoothest, and healthiest skin you've ever felt and seen.

girl applying serum for dark circle

First off, what is Matrixyl 3000?

Good question, and one that should be addressed before we can discuss Matrixyl 3000's benefits. Matrixyl 3000 is a peptide made up of two proteins, to put it simply. If you're unfamiliar with the term, a peptide is a protein that serves as one of our cells' building components. To put this in perspective, peptides are required for stimulating cell activity. Like mentioned above, it is a robust anti aging ingredient packed with Amino Acids, vital to the growth and maintenance of collagen.

Unfortunately, as we age, our peptides lose their ability to interact effectively, resulting in wrinkles, sagging skin, and dullness. So, does Matrixyl Serum really work? In the aid of the battle against ageing skin?​

Let's talk about it.​

The Origin of Matrixyl

Matrixyl is a trademark of Sederma, a cosmetic ingredient development firm. It was established using a series of anti-wrinkle actives that comprise Matrikine, a peptide that aids the proper functioning of many components of the skin's structure.

It became a tremendously popular and well-known active ingredient in the personal care market, notably in the anti-aging sector, after its introduction in 2000.

Another name for Matrixyl? The Scientific name for Matrixyl that is Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) Matrixyl 3000 which is made from a combination of Palmitoyl Tripeptide-7 and Palmitoyl-Oligopeptide

What are the Benefits of Matrixyl 3000 Serum?

  • Supports Collagen Production

If you're familiar with anti-aging, you're aware of the importance of collagen.The body produces collagen naturally, however as we get older, our collagen synthesis diminishes, resulting in ageing indications.

Matrixyl 3000 comes into play here. Our Matrixyl 3000 Collagen Boosting Serum will assist encourage the development of new collagen to help bring life back to your sagging skin if you've lost any collagen. Collagen, in particular, aids in the restoration of plumpness.

  • Improves the Apperance of Wrinkles

If you're as obsessed with anti-aging as we are, you already know that plumper skin (thanks to collagen) and improved moisture (thanks to hyaluronic acid) will make your skin seem less wrinkled. It's that simple.

  • Enhanced Glow 

We all want glowing skin, and thankfully, achieving that glow is more attainable than we may think. To put it simply, glow is all about moisture. If your skin is dehydrated, you’ll look dull and tired. If your skin is moisturised, you’ll look lively and youthful. Matrixyl 3000 helps to replenish moisture in exhausted skin cells, improving the shine and vitality of your skin.


  • Non-Irritating and Suitable for Sensitive Skin 

All too often, anti-aging products are formulated with some of the harshest, most irritating ingredients. Thankfully, this isn’t the case with Matrixyl 3000. Our formulation with this ingredient is gentle and won’t irritate even the most sensitive skin - with no reported side effects! In a recent survey of 500 users, 96.2% said they had no reactions to our Matrixyl 3000 Serum.

In other words, Matrixyl 3000 is safe and effective to use on almost all skin types.


Dēpology‘s Best Pairing Products :

The  Micro Dart Treatment Boosting Serum works optimally together with our Deepcare+ Micro-Dart Patches to boost the effects of the patches and multiply the speed of the production of collagen in the skin matrix and dermal. With the help of our Retinol night cream that deeply nourishes around your skin without it feeling greasy. It also helps to speed up cellular turnover and bring your skin back to a more youthful state around your face. It is a potent anti-aging agent which helps to firm the skin as well as dramatically reduce fine lines and wrinkles resulting in firmer younger looking skin. This trio anti-aging product is also suitable for dry skin as well as sensitive skin types. While effective on its own, combine with our Micro-Dart patches & Retinol night cream for the most effective & radiant results.

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How to Use : Dēpology’s Matrixyl 3000 Serum

How to layer Matrixyl? 

  1. Thoroughly cleanse and tone the skin
  2. Apply a few drops of Matrixyl Serum onto your palm and massage gently onto your face. Make sure to apply generously to areas where age lines form easily such as the forehead and around the eyes.
  3. After the serum has absorbed fully into the skin, apply your favourite Micro- Dart patches. Once in contact with the skin, the Micro-Data will start to dissolve and activate the serum into the skin.
  4. Apply Dēpology‘s Retinol Face Cream to the face to help seal in key ingredients. If you are wearing patches, apply the moisturiser around the patches.

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Dēpology’s Uniquely Formulated Serum  

Our Matrixyl 3000 serum has been specially formulated with premium ingredients to activate and optimize your micro dart treatment. Designed to target and slow down wrinkle formation whilst promoting the production of collagen in the skin matrix and dermal. Matrixyl 3000 has multiple key benefits all leading to younger and healthier looking skin.

In our recent user survey, ¾ of all users reported noticeable benefits within 3-4 weeks of using our Matixyl 3000 Serum. Doctor & Dermatology Registrar Dr.Emma Amaofo Mensah noted that "Most products take a minimum of 4 weeks for people to notice effectiveness, with peal effectiveness often being noticed at 3 months."​.

This matrixyl synth also works well in combination with other anti wrinkle and skincare products.

Matrixyl 3000 ingredients

Contains Matrixyl 3000

Matrixyl 3000 is a type of synthetic peptide used in skin care for its scientifically-proven ability to stimulate collagen production, which results in anti-aging effects. Matrixyl 3000 is composed of matrikines which work synergistically to restore the skin’s youthful appearance by signalling to cells to produce more collagen.

Hyaluronic Acid skincare ingredients

Contains Hyaluronic Acid

In a similar vein, Matrixyl 3000 also helps with the production of hyaluronic acid, which again, is something your body naturally produces to help with moisture retention; however, as we age, the amount of hyaluronic acid we produce decreases.

With Matrixyl 3000 in your skincare arsenal, you don’t have to worry about this depleted supply. Regular use of products containing Matrixyl 3000 will increase hyaluronic acid, ensuring skin looks moisturised, bright, and youthful.

Read this article to learn more about the benefits of hyaluronic acid.

Glycerin skincare ingredients

Contains Glycerin

Glycerin works as a humectant, it attracts moisture from the air into the top layer of skin, and due to its low molecular weight it has the ability to penetrate into the deeper layers of the skin delivering moisture to these areas.

Aloe Barbadensis skincare ingredients

Contains Aloe Barbadensis

Rich in vitamins A, C, D, and E, and packed with minerals, like zinc, potassium, and magnesium. This ingredient promotes healing in the skin while creating a barrier that helps moisturise and protect the skin.

Is Matrixyl better than Retinol?

Anti-aging skin care chemicals such as Retinol and matrixyl are among the various options available to consumers. Choosing the right components for your skin might be difficult. Especially when you evaluate all of your possibilities. Also, keep in mind that they battle fine lines and wrinkles in somewhat different ways.

As you put together an anti-aging skin-care routine! Perhaps you're perplexed by the distinction. Is Matrixyl the same as Retinol? Retinol is a vitamin A-derived natural skin care component. Matrixyyl, on the other hand, is a blend of synthetic peptides.

A Question asked often by consumers in the skincare industry, can you use Matrixyl with Retinol? You are also receiving the collagen-building effects of vitamin A.” Additionally, retinol also works to improve the penetration of peptide creams and serums which can help improve skin firmness. When combined, you'll improve the efficacy. If you've comfortably incorporated a retinol or retinoid product into your routine, there's no need to throw out your retinol! Matrixyl and retinol work well together.

While both may aid in the attainment of your skin care goals, one may be more effective than the other. This is dependent on your skin type and the conditions you're seeking to resolve.

Why Choose Dēpology’s Matrixyl Collagen Boosting Serum?

In a recent user survey with 500 particpants conducted by Depology - 86% of consumers experienced substantial benefits to their skin after using our Matrixyl Serum, with the majority of users seeing 2+ primary skin benefits. Hydrated skin, improved texture, wrinkle reduction, and firmer skin were amongst the achieved effects.

"The results of the survey are impressive. 500 respondents is a good cohort size, and over 73% of the respondents rated the product 8/10 or above in terms of effectiveness. It’s also very encouraging that 96% of respondents didn’t experience any adverse reactions" concluded Dr Emma Amaofo who reviewed our surveying process and results.

The answer should be relatively obvious, but just so we’re all on the same page about the effectiveness of this serum. What Dēpology products have Matrixyl in them? We’ve added Matrixyl 3000 to Dēpology ‘s Collagen Boosting Serum to help reduce the appearance of wrinkles by copying the behaviour and patterns of damaged collagen with the use of peptides. So these peptides are powerful cells communicating ingredients, and when they communicate that collagen has been damaged, this kicks the body's healing abilities into action.

In conclusion, Matrixyl 3000 helps bring back necessary moisture to depleted skin cells, helping to improve glow and your skin's vibrancy for your naturally beautiful look.

Make sure your face is radiant and full of life by utilising the benefits of our Dēpology Full Range of Anti ageing Products. Try our products now! You won’t be disappointed!

Thoughtfully designed products. Thoroughly selected ingredients. All with our community in mind. That is how we do it at Dēpology.