How Does Argireline™ Work?: Clinical Trial Results

In the pursuit of youthful and radiant skin, skincare enthusiasts are always on the lookout for innovative products. One such product that has recently undergone rigorous clinical trials is the Depology Peptide Complex Serum containing Lubrizol 10% Argireline™ Complex. Let's dive into the findings of these clinical trials to understand the efficacy of this serum in improving periorbital wrinkles and skin moisturization.

methodology: Trials & Evaluation

At Depology, we believe in the power of scientifically-backed skincare that delivers tangible results. Our research began with a meticulous screening process, ensuring that participants met the inclusion criteria and were free from any exclusion factors.

The clinical trial was conducted at the OATC Skin Clinical Trial Center in Korea. A total of 20 Korean adult women aged 30 to 60 were enrolled in the study. The participants were randomly assigned to use the Depology Peptide Complex 10% Serum for four weeks.

Held within controlled temperature (20~24”C, 40~60% humidity) condition, Before beginning the research, each person in the study used the same cleaner and then rested for 30 minutes in controlled temperature and humidity levels. This meticulous approach set the stage for a truly groundbreaking exploration. Keep on reading for the results.

The efficacy of the serum was assessed using two methods:

  1. Antera 3D® CS: This device was used to measure the depth of periorbital wrinkles.

  2. Epsilon E100: This device was used to measure skin moisture levels.

1# Periorbital Wrinkle testing: Antera 3D® CS

Assessment: One of the key aspects we explored was the serum's impact on periorbital wrinkles—the delicate lines around the eyes that often reveal the passage of time. We employed cutting-edge technology called Antera 3D® CS to measure and analyze the selected area around the left eye of our participants. The Wrinkle Indentation Index (A.U.) became our guide, showcasing the intensity of wrinkles in that region. And guess what? The results were nothing short of remarkable!

Results: Periorbital Wrinkle Improvement.
After four weeks of consistent use, the Wrinkle Indentation Index demonstrated an impressive decrease of 7.2%. Imagine bidding farewell to those unwanted lines and welcoming smoother, more youthful-looking skin. Yes, it's possible with the Depology Peptide Complex 10% Serum!

See the table below for the assessment results

2# Skin Moisture Testing:
Epsilon E100

Assessment: We all crave that coveted "lit-from-within" glow, and healthy skin moisture plays a vital role in achieving it. To assess the serum's impact on skin hydration, we turned to the trusty Epsilon E100 device. Focusing on the left cheek area, we measured the moisture level using the Epsilon value. The higher the value, the brighter and more hydrated the skin appeared in the resulting image. Prepare to be amazed by these results!

Results: Skin Moisture Improvement
After just four weeks of product usage, the skin moisture level showed a jaw-dropping increase of 45.68%. That's right, the serum worked its magic, leaving skin deeply hydrated, radiant, and positively glowing. Prepare to embrace a complexion that captivates and reflects your inner beauty!

See the table below for the assessment results

side effects of Argireline™: Adverse Reactions Assessment


We understand your concerns about skincare safety. Rest assured, our dedicated team of experts conducted a comprehensive assessment of potential adverse reactions. We closely examined the skin where the research product was used and engaged in insightful interviews with our participants. The fantastic news? Not a single skin abnormality or adverse reaction was observed among the 20 participants who completed the study. Your trust in the Depology Peptide Argireline™ Complex Serum is well-placed, as it has been proven to be safe for your precious skin.

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See the table below for the assessment results

Peptide Complex 10% Argireline™ peptide Serum

Unveil the Secret to Ageless Beauty with Depology Peptide Complex 10% Argireline™ Serum. Our potent formula, enriched with Argireline™ peptide and Hyaluronic Acid, targets and prevents wrinkles while intensely hydrating your skin. Clinically tested and proven, this advanced serum seamlessly integrates into your skincare routine, revealing radiant and youthful-looking skin. Experience the transformative power of science-backed skincare and unlock ageless beauty with Depology.

final verdict: Does Argireline™ really work?


Yes! Results don't lie, this research was conducted under contract from a corporation Geumsan Online Consulting and evaluated the effects of the serum on periorbital wrinkle improvement and skin moisturization in 20 Korean adult women aged 30 to 60. The results of the study are summarized as follows:

  • Periorbital Wrinkle Improvement: After four weeks of using the Depology Peptide Complex Serum, the indentation index value representing the wrinkle index showed a significant decrease of 7.2%. This decrease indicates an improvement in periorbital wrinkles.

  • Skin Moisture Improvement: After four weeks of product usage, the skin moisture level exhibited a significant increase of 45.68%. This increase suggests improved skin moisturization.

The Argireline™ results of this clinical trial provide compelling evidence of the remarkable benefits offered by the Depology Peptide Complex Serum containing Lubrizol 10% Argireline™ Complex. The serum demonstrated its efficacy in improving periorbital wrinkles, as evidenced by a significant decrease in the Wrinkle Indentation Index.

Additionally, it showcased its ability to enhance skin moisturization, with a substantial increase in the skin moisture level. These findings are a testament to the power of advanced skincare technology and the meticulous research conducted at the OATC Skin Clinical Trial Center.

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