Can You Use Argireline™ Serum With?: You Asked, We Answered

Have you ever wondered how you can keep your skin looking gorgeous without resorting to invasive procedures? You're not alone! Many people are turning to alternative skin treatments, like Peptide Complex 10% Argireline™ Peptide Serum, to help minimize fine lines and wrinkles. But can you use Argireline™ with other skincare ingredients, or is it best to go solo?

In this blog post, we'll dive into the the most asked questions of Argireline™, breaking down what to and what not to pair it with to take your skincare routine to the next level. So grab a cup of tea and let's get started!


Yes, you can use Argireline™ with niacinamide. Argireline™ is a popular ingredient used in skincare products to help minimize the appearance of fine lines and wrinkles by relaxing facial muscles. Niacinamide, on the other hand, is a form of vitamin B3 known for its ability to improve skin texture, calm inflammation, and regulate oil production. These two ingredients work well together and can be incorporated into your skincare routine. If you're going after those expression line areas, put Peptide Complex 10% Argireline™ Peptide Serum on first. niacinamide should come after.


Depology's Dark Spot Correcting N.A.T Serum, is a powerful serum created to treat skin discolouration, age spots, and abnormal pigmentation. Additionally, this serum includes tranexamic acid, a pigment blocker that aids in preventing new hyperpigmentation from forming. |

Every morning and evening, after cleaning and toning the skin, use this serum, being sure to wear sunscreen during the day.


Yes, you can use Argireline™ with Tretinoin. However, it is important to start slowly and gradually increase the amount of product that you use. Tretinoin can be irritating to the skin, so it is important to use it with caution.

If you are using Argireline™ and Tretinoin, it is also important to use a sunscreen every day. Tretinoin can make your skin more sensitive to the sun, so it is important to protect your skin from sun damage.

What are the primary differences between retinol and tretinoin. While tretinoin is a synthetic version of vitamin A, retinol is naturally generated from that vitamin. Tretinoin is far more potent than retinol. While retinol compounds are commonly available over the counter, tretinoin requires a prescription.



Argireline™ and Vitamin C are two popular skincare ingredients that are often used to reduce the appearance of creased and saggy skin. But can you use them together?

The answer is yes, but with caution. Why?
Argireline™ is a peptide that works by blocking the signals that cause muscles to contract. This can help to smooth out the appearance of wrinkles caused by facial expressions. Vitamin C is an ascorbic acid antioxidant that helps to protect the skin from damage caused by free radicals.

However, Argireline™ should not be used with direct acids, such as L-ascorbic acid (LAA) or ethylated ascorbic acid (EAA). This is because direct acids can irritate the skin, and using them with Argireline™ could increase the risk of irritation." Dermatologist Dr. Sina Ghadiri does not recommend pairing our two products together due to the clash of ingredients that may cause irritation to your skin. "

Vitamin C & Argireline™ is not compatible with direct acids. However, it is safe to use vitamin C with other types of antioxidants, such as ferulic acid or vitamin E.


The most effective way to maximise anti-aging effects of these two ingredients is to apply them on different days of the week, depending on your skin's condition.

☀️ AM: Why we recommended applying Vitamin C serum in the morning because of its advantageous benefits, including preventing UV damage, hyperpigmentation, circulation, brightening skin, aiding in the healing of surface damage.

🌙 PM: Because the two peptides in our Depology formulation act together synergistically, we recommended utilising Argireline™ at night in addition to your Matrixyl® 3000 serum. The benefits of Peptide Complex 10% Argireline™ Peptide Serum work by suppressing nerve impulses that tell muscles to contract and by smoothing out the appearance of wrinkles brought on by facial expressions. Matrixyl® 3000 serum should then be applied after that in order to assist replenish the skin moisture.

It is often used in the morning to provide antioxidant protection throughout the day. Argireline™ can be used at night to target muscle contractions and minimize the appearance of expression lines. By incorporating both ingredients into your skincare routine, you can address multiple skin concerns effectively.

No matter how you choose to use them, it is important to patch test both Argireline™ and vitamin C before using them on your face. This will help to determine if you are allergic to either ingredient.

Watch NatashaBeautyJunkieMonkey TikTok Video: Vitamin C with Argireline


Glycolic acid, a common alpha hydroxy acid (AHA) renowned for its exfoliating qualities and Argireline™ works well together. Dead skin cells are removed, skin texture is improved, and cell turnover is promoted with glycolic acid. You can apply glycolic acid at night and Argireline™ in the morning/night also, or you can apply both at once and wait 30 minutes in between. This enables the goods to function properly without generating any discomfort or irritation.


Yes absolutely, hyaluronic acid is a hydrating ingredient that helps retain moisture in the skin, keeping it plump and hydrated. It is safe to use hyaluronic acid with Argireline™. You can use Argireline™ in at night to target muscle contractions, while hyaluronic acid can be used in the morning and night to provide hydration and support the skin's moisture barrier. Alternatively, you can use both ingredients at the same time of the day, as they have complementary benefits.



The answer to the frequently asked question, "Can you mix Argireline™ with other skincare ingredients?" is a resounding YES! Argireline™ is a versatile ingredient that can be combined with various skincare companions to maximize its benefits. Whether it's pairing it with hyaluronic acid for hydration or combining it with peptides for plumpling effects, mixing Argireline™ opens up a world of possibilities for personalized skincare.

However, it's essential to approach mixing with caution. Before diving into a new skincare cocktail, perform patch tests to ensure compatibility and avoid any potential adverse reactions. Applying a small amount of the mixed products to a discreet area will help you determine if the combination works well for your skin.

By experimenting with Argireline™ and compatible skincare ingredients, you have the opportunity to create a customized routine that targets your specific skincare concerns. Remember, skincare is a personal journey, and finding the right combination of ingredients that works for you is key. Consider seeking advice from skincare professionals or experts if you have any concerns or questions along the way. Embrace the potential of mixing Argireline™ and unlock the transformative results that await you on your skincare journey.