See why it's going viral!
Save Over 10%
4 Reasons Everyone Loves Minimal Line Peptide Serum Duo

1.Dermatologist-Recommended Dual Formula
This serum duo works. But don’t just take our word for it—dermatologists recommend it for visibly firmer, younger-looking skin.
2. Prevention & Correction in One System
A dual-peptide approach: one serum helps prevent fine lines, while the other smooths deeper wrinkles for comprehensive anti-aging care.
3. Clinically Proven to Reduce Wrinkles
Powered by Matrixyl® 3000 and Argireline™, these potent actives are clinically proven to visibly improve fine lines and expression wrinkles.
4. Boosts Hydration & Radiance
Infused with Niacinamide and Hyaluronic Acid to strengthen the moisture barrier, visibly refine skin texture, and enhance overall glow.
Proven Results
95%
said their skin feels smoother and more hydrated
92%
said the appearance of fine lines and wrinkles visibly improved
87%
said their skin looks firmer and more lifted
Before and After 60 Days of Use
When used as directed. Unedited and not retouched. Results may vary.
Full Description
This product is recommended for those looking to:
- Target the appearance of fine lines around the mouth, eyes, and forehead
- Promote a firmer, smoother, and more youthful-looking complexion
- Improve skin hydration and overall skin texture
Why Minimal Line Peptide Serum Duo?
Treat yourself to our best-selling anti-aging serum duo. While this isn’t a miracle cure, we’ve combined two powerful serums with clinically proven peptides to address both fine lines and deeper wrinkles for smoother, firmer skin.
It’s gentle, non-greasy, non-comedogenic, and fits seamlessly into any skincare routine!

Cruelty Free

Dermatologist Recommended

Paraben Free

Gluten Free

Synthetic
Fragrance Free

Synthetic Color
Free
Directions
- Apply 4-5 drops onto fingertips and gently smooth over a slightly damp face. Apply the Peptide Complex 10% Serum on problem areas. Follow with Matrixyl® 3000 Collagen Serum to visibly smooth fine lines and wrinkles.
- Allow the product to absorb fully before applying additional skincare.
- Use twice daily or as directed by your physician.
Ingredients
Ingredient Highlights
Argireline™ peptide, Matrixyl® 3000
All Ingredients
Argireline™ 10%, Vita-Polypeptide, K-Science Blend (Including Cica, Heartleaf, Fig Extract, And Camomile Flower Oil), Vitamin E, Matrixyl 3000, Hyaluronic Acid, Collagen, Aloe Barbadensis.
Skin Concerns

Wrinkles

Fine lines

Firmness

Hydration

Normal
Skin Type

Normal

Dry

Combination

Oily
The Perfect Additions to Any Routine

Deepcare+ Serum-Infused Micro Dart Patches (8 pairs)
5313 reviews
$66
$72
8 pairs
Supercharged Micro-Dart Patches that reduce the appearance of fine lines and wrinkles while hydrating the skin.

Opuntia-C™ Relief Cleansing Balm
24 reviews
$36
$72
100ml
Created with Korean Cactus and is designed especially for delicate skin.

Moisturizing Caviar Multi Balm Stick
579 reviews
$30
$72
10.5g
Formulated with Caviar and supercharged hydrating ingredients.

Matriplex™ Peptide Intense Cream
377 reviews
$62
$72
50ml
This Peptide Complex Eye Cream, meticulously formulated with Argireline™ peptide.
What are people saying about these serums
Anna***
Verified User

My skin get compliments daily
This has been the most rewarding well spent money ever. My skin get compliments daily. Now my neighbor, my nursing colleagues are ordering your products. I don't want to be without these life changing serums.
Bruhn***
Verified User

I just love how my skin glows after every use
I work in the medical health field and wearing a mask all day use to dry up my skin on top of already bad skin. But after starting Depology, masks dont bother me much
Melissa***
Verified User

The products are so gentle yet effective
The products are so gentle yet effectiveand and my complexion has never looked better. I highly recommend them to anyone looking for a reliable, science-backed skincare routine!
Jac***
Verified User

The results are unbelievable!
I’ve been using Depology’s anti-aging products for a month, and the results are unbelievable! My fine lines are visibly reduced, and my skin looks firmer and more youthful. I love that these products are gentle yet powerful.
For the first time in a long time I love what I see in the mirror!! I’m 49 years old and was looking tired. Now no one believes I’m in my late 40s, everyone thinks I’m in my 30s. Can’t believe how quickly I saw results.
I was skeptical but I have been using this since dec 26th and my skin has noticeably less fine lines and appears smoother
As a post-menopausal woman, I have the need to boost my collagen production and reduce the appearance of fine lines. Getting two serums that you can layer to address both issues at this price is a great value.
The serums do not come with any instructions but I believe that the company assumes you know that you can layer them? Anyway, I really like the dispenser because where the dropper comes out of the bottle there is a plastic ring that provides a tight seal so nothing can get into the bottle.
You only need about 3 drops, so these bottles will last months. After I wash and tone my face, I start with the collagen boosting (Matrix 3000) and then the wrinkle defense (Peptide Complex). I wait a good 10 minutes before I put on my moisturizer.
Frequently Asked Questions
How do I use Minimal Line Peptide Serum Duo?
- Cleanse your face and pat dry.
- Follow with a few drops of Corrector Serum (Matrixyl® 3000), focusing on deeper wrinkles and areas needing repair.
- Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum can be used with retinol. They complement each other well, enhancing the overall benefits for your skin.
Can these serums be paired with Retinol or Retinoids?
Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum can be used with retinol. They complement each other well, enhancing the overall benefits for your skin.
Should I use these serums on damp or dry skin?
For best results, apply the serums on damp skin. This helps with better absorption and maximizes the effectiveness of the active ingredients.
How often do I need to use these serums?
Both serums can be used daily, preferably twice a day—morning and night—for best results. Consistency is key to seeing noticeable improvements in skin texture and appearance.
Are these serums suitable for all skin types?
Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum are suitable for all skin types. They are formulated to be gentle yet effective, providing anti-aging benefits without irritation.
Best Selling Bundles

Anti-aging Trio Set
144 reviews
The ULTIMATE anti-aging power trio for noticeably youthful-looking skin.

Matrixyl® Trio Bundle
31 reviews
Designed to provide intense hydration, help reduce the appearance of aging signs.

Age-deying Peptide Ensemble
76 reviews
This collection features the year's top skincare essentials, expertly chosen to enhance your routine.

Peptide Duo + Caviar Stick
1026 reviews
Rejuvenate your skin with high-performing, promising formulas that work together to keep your skin hydrated and nourished,