[PEPTIDE DUO - USE DAY AND NIGHT]
Depology Peptide-Serum Duo
$80
$89
Depology’s Peptide Serum Duo includes two signature serums that blend potent peptides with effective ingredients to reduce the appearance of both static and dynamic wrinkles, enhancing a youthful and hydrated glow.
PRODUCT INFORMATION
Peptide Complex 10% Wrinkle Defense Serum
A potent serum formulated with Argireline™ peptide, known for its ability to support a more relaxed look of facial expressions, effectively improving the appearance of dynamic lines.
Matrixyl® 3000 Collagen Serum
A supercharged serum containing 5% Matrixyl® 3000, designed to minimize the look of deep static wrinkles and support a collagen-rich skin appearance.
Disclaimer ↓
The Content, statements, and other material made available on or through the Site: (i) are not intended to diagnose, treat, cure, or prevent any medical condition or disease; and (ii) are not in any way intended as medical advice or as a substitute for medical treatment.
BENEFITS & WHY CHOOSE
- Minimizes the appearance of both static and dynamic wrinkles
- Delivers hydration for a plump, smooth appearance
- Helps protect the skin from environmental stressors
-
Suitable for all skin types, including sensitive skin
Depology Peptide Serum Duo is designed to offer an integrated solution that single products cannot match.
Each serum effectively works on different types of wrinkles on its own. When used together, they enhance each other’s benefits, resulting in more noticeable and long-lasting improvements in skin texture and overall appearance.
HOW TO USE
Step [1]
Cleanse and tone skin to prepare for treatment.
Step [2]
Apply Peptide Complex 10% Serum
Apply Peptide Complex 10% Serum to areas with dynamic wrinkles, such as crow's feet and forehead lines. Wait until fully absorbed.
Step [3]
Follow with Matrixyl® 3000 Collagen Serum
Follow with Matrixyl® 3000 Collagen Serum, applying it all over the face, including the neck area.
Shipping policy
We ship worldwide. We provide customers from the USA and International postal tracking via email.
Paraben Free
Gluten Free
Synthetic Fragrance Free
Synthetic Color Free
· Matrixyl® 3000 Collagen Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml
· Matrixyl® 3000 Collagen Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml
4 interest-free payments with Learn more
Shipping policy
We ship worldwide. We provide customers from the USA and International postal tracking via email.
Paraben Free
Gluten Free
Synthetic Fragrance Free
Synthetic Color Free
IN THIS DUO SET
ORIGINAL VALUE - $89.00
Bundle Price - $80.00
Targets
Dynamic lines
Elasticity loss
Suited For
Dull and dry skin
Benefits
- Reduces dynamic wrinkle appearance
- Improves skin texture
- Enhances skin moisture
Disclaimer ↓
About Argireline™ peptide:
Argireline™ peptide is a trademark of Lubrizol Advanced Materials, Inc.
Targets
Static lines
Firmness loss
Suited For
Sensitive and dehydrated skin
Benefits
- Reduces static wrinkle appearance
- Supports a more youthful appearance
- Contributes to a healthy glow
Disclaimer ↓
About Matrixyl® 3000：
Matrixyl® 3000 is a trademark of Sederma Inc and neither Depology Holdings nor Depology Skincare is affiliated with Sederma Inc.
SEE THE TRANSFORMATION FROM OUR REAL CUSTOMERS!
"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."
@beauty**
"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."
@beauty**
"For the first time in a long time I love what I see in the mirror!! I’m 49 years old and was looking tired. Now no one believes I’m in my late 40s, everyone thinks I’m in my 30s. Can’t believe how quickly I saw results."
@@robiny**
SEE THE TRANSFORMATION FROM OUR REAL CUSTOMERS!
"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."
@beauty**
"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."
@beauty**
For the first time in a long time I love what I see in the mirror!! I’m 49 years old and was looking tired. Now no one believes I’m in my late 40s, everyone thinks I’m in my 30s. Can’t believe how quickly I saw results.
@robiny**
[1] DYNAMIC WRINKLES
Dynamic wrinkles are caused by repetitive facial movements such as smiling, frowning, or squinting. These wrinkles typically appear in areas with frequent muscle activity and are most commonly seen as:
- Frown lines
- Forehead lines
- Crow's feet
[1] DYNAMIC WRINKLES
Dynamic wrinkles are caused by repetitive facial movements such as smiling, frowning, or squinting. These wrinkles typically appear in areas with frequent muscle activity and are most commonly seen as:
- Frown lines
- Forehead lines
- Crow's feet
Argireline™ peptide
Argireline™ peptide is a powerful ingredient known for its ability to target dynamic wrinkles. It can help to relax the appearance of expression lines and smoothing the skin.
[2] STATIC WRINKLES
Static wrinkles are the result of the natural aging process, including the loss of skin elasticity and collagen over time. These wrinkles are present even when the face is at rest and typically appear as
- Smile lines
- Cheek lines
- Marionette lines
[2] STATIC WRINKLES
Static wrinkles are the result of the natural aging process, including the loss of skin elasticity and collagen over time. These wrinkles are present even when the face is at rest and typically appear as
- Smile lines
- Cheek lines
- Marionette lines
Matrixyl® 3000 Peptide
Matrixyl® 3000 is a renowned peptide complex known for its ability to promote a smoother look and improve skin texture, contributing to a firmer appearance. This advanced formula helps reduce the visible signs of aging, providing a more youthful and revitalized complexion.
[1] DYNAMIC WRINKLES
Dynamic wrinkles are caused by repetitive facial movements such as smiling, frowning, or squinting. These wrinkles typically appear in areas with frequent muscle activity and are most commonly seen as:
- Frown lines
- Forehead lines
- Crow's feet
Argireline™ peptide
Argireline™ peptide is a powerful ingredient known for its ability to target dynamic wrinkles. It can help to relax the appearance of expression lines and smoothing the skin.
[2] STATIC WRINKLES
Static wrinkles are the result of the natural aging process, including the loss of skin elasticity and collagen over time. These wrinkles are present even when the face is at rest and typically appear as
- Smile lines
- Cheek lines
- Marionette lines
Matrixyl® 3000 Peptide
Matrixyl® 3000 is a renowned peptide complex known for its ability to promote a smoother look and improve skin texture, contributing to a firmer appearance. This advanced formula helps reduce the visible signs of aging, providing a more youthful and revitalized complexion.
RECOMMENDED BY SKINCARE PROFESSIONALS
Dr. Anthony Youn
Board-certified plastic surgeon
“They are both premium Korean peptide serums known for their science-backed formulas and luxurious feel on the skin.”
Dr. Laura Soong
Board Certified Dermatologist
“I highly recommend you give this wrinkle best combination a try!”
Dr. Sanya Kundra
Medical Cosmetologist
“The serum is lightweight, absorbs quickly, and leaves my skin feeling incredibly hydrated and smooth. My skin feels firmer and looks more radiant—exactly what I was hoping for!”
Dr. Taewoon Kim
Board-certified plastic surgeon
"I first used these two Depology products two years ago, and I noticed an improvement in the appearance of the wrinkles in my under-eye area.”
CLINICAL TRIAL RESULTS AFTER JUST 4 WEEKS OF USE
Wrinkle index decreased by
7.22%
Wrinkle index decreased by
7.22%
Skin hydration increased by
46.31%
Skin hydration increased by
46.31%
HOW TO USE
Step [1]
Thoroughly cleanse and tone the skin.
Step [2]
Argireline Serum [Peptide Complex 10% Serum]
Apply 3-4 drops of serum onto your palm and gently massage it onto the face, focusing on dynamic wrinkle areas such as: Frown lines, Forehead lines and Crow's feet.
Step [3]
Matrixyl 3000 Serum
Let the Argireline Serum absorb for 1-2 minutes. Then apply 3-4 drops of Matrixyl 3000 serum onto your palm and gently massage it onto the face, focusing on static wrinkle areas such as: Smile lines, Cheek lines and Marionette lines.
Step [4]
Let the Matrixyl 3000 Serum absorb and follow up with your favorite moisturizer.
RECOMMENDED BY SKINCARE PROFESSIONALS
Dr. Anthony Youn
Board-certified plastic surgeon
“They are both premium Korean peptide serums known for their science-backed formulas and luxurious feel on the skin.”
Dr. Laura Soong
Board Certified Dermatologist
“I highly recommend you give this wrinkle best combination a try!”
Dr. Sanya Kundra
Medical Cosmetologist
“The serum is lightweight, absorbs quickly, and leaves my skin feeling incredibly hydrated and smooth. My skin feels firmer and looks more radiant—exactly what I was hoping for!”
Dr. Taewoon Kim
Board-certified plastic surgeon
"I first used these two Depology products two years ago, and I noticed an improvement in the appearance of the wrinkles in my under-eye area.”
HOW TO USE
Step [1]
Thoroughly cleanse and tone the skin.
Step [2]
Argireline Serum [Peptide Complex 10% Serum]
Apply 3-4 drops of serum onto your palm and gently massage it onto the face, focusing on dynamic wrinkle areas such as: Frown lines, Forehead lines and Crow's feet.
Step [3]
Matrixyl 3000 Serum
Let the Argireline Serum absorb for 1-2 minutes. Then apply 3-4 drops of Matrixyl 3000 serum onto your palm and gently massage it onto the face, focusing on static wrinkle areas such as: Smile lines, Cheek lines and Marionette lines.
Step [4]
Let the Matrixyl 3000 Serum absorb and follow up with your favorite moisturizer.
CUSTOMER TESTIMONIALS
Highly recommend!
“I live in a city with very dry climate. This peptide combo gives me the moisture my skin needs. The caviar stick is also great. I carry it and use it when i need that extra moisture. My skin has improved since using Depology products. Highly recommend! ”
- TBUI
☑Verified Buyer
My skin has never been so healthy and smooth.
“Since using my Depology serums and products I have gotten so many compliments and questions as to what I use . My skin has never been so healthy and smooth you can see a big difference in texture along with minimal wrinkles . People ask me how at 70 do I manage to look younger ! I’ve recommended Depology to my family too! ”
- Henry Cruz
☑Verified Buyer
My skin looking the best it ever has!
“The combination of these products has my skin looking the best it ever has! My skin stays looking hydrated and plump throughout the entire day!”
- Linda Mitchell
☑Verified Buyer
I love the way it feels on my skin.
“I have been using Peptide Serum Duo for about a month. I love the way it feels on my skin and I am seeing better skin texture and suppleness.”
- Tracy
☑Verified Buyer
I love this serum.
“I love this serum. I keep getting compliments on how dewy and healthy it looks. I am 48 years old and I have not taken great care of my skin until recently. This serum is changing the texture, tone, and it feels soft to touch.”
- Lawreen
☑Verified Buyer
CUSTOMER TESTIMONIALS
Highly recommend!
“I live in a city with very dry climate. This peptide combo gives me the moisture my skin needs. The caviar stick is also great. I carry it and use it when i need that extra moisture. My skin has improved since using Depology products. Highly recommend! ”
- TBUI
☑Verified Buyer
My skin has never been so healthy and smooth
“Since using my Depology serums and products I have gotten so many compliments and questions as to what I use . My skin has never been so healthy and smooth you can see a big difference in texture along with minimal wrinkles . People ask me how at 70 do I manage to look younger ! I’ve recommended Depology to my family too! ”
- Henry Cruz
☑Verified Buyer
My skin looking the best it ever has!
“The combination of these products has my skin looking the best it ever has! My skin stays looking hydrated and plump throughout the entire day!”
- Linda Mitchell
☑Verified Buyer
I love the way it feels on my skin
“I have been using Peptide Serum Duo for about a month. I love the way it feels on my skin and I am seeing better skin texture and suppleness. ”
- Tracy
☑Verified Buyer
I love this serum.
“I love this serum. I keep getting compliments on how dewy and healthy it looks. I am 48 years old and I have not taken great care of my skin until recently. This serum is changing the texture, tone, and it feels soft to touch.”
- Lawreen
☑Verified Buyer
FAQ
Can I use one serum that includes both Matrixyl® 3000 and Argireline™ peptide?
No, we recommend using the serums separately for optimal results. Apply Peptide Complex 10% Argireline™ Peptide Serum first and wait until it is fully absorbed before applying Matrixyl® 3000 Collagen Serum. This method ensures each ingredient works effectively on its targeted wrinkles.
Can these serums be paired with Retinol or Retinoids?
Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum can be used with retinol. They complement each other well, enhancing the overall benefits for your skin.
Should I use these serums on damp or dry skin?
For best results, apply the serums on damp skin. This helps with better absorption and maximizes the effectiveness of the active ingredients.
How often do I need to use these serums?
Both serums can be used daily, preferably twice a day—morning and night—for best results. Consistency is key to seeing noticeable improvements in skin texture and appearance.
Are these serums suitable for all skin types?
Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum are suitable for all skin types. They are formulated to be gentle yet effective, providing anti-aging benefits without irritation.
COLLAGEN SERUM
MATRIXYL® 3000 COLLAGEN SERUM
★★★★★ [3000+ Reviews]
✓ Improves hydration by 46.31% | ✓ Makes the skin plump and glowy
[USE TWICE DAILY]
A supercharged plumping serum formulated with Matrixyl® 3000, designed to help reduce the appearance of aging signs and promote a youthful, hydrated glow.
About Matrixyl®
Matrixyl® is a trademark of Sederma Inc and neither Depology Holdings nor Depology Skincare is affiliated with Sederma Inc.
KEY INGREDIENTS
MATRIXYL 3000
Rejuvenating
Our core ingredient, formed from two peptides that work synergistically to restore and maintain the skin’s youthful characteristics.
HYALURONIC ACID
Hydrating
Our core ingredient, aids in the binding of water to collagen, retaining it in the skin for a plumper, and more hydrated appearance.
COLLAGEN
Plumping, Nourishing
This innovative collagen extract from yeast is synergistic with natural collagen, visibly diminishing signs of aging and delivering moisturizing benefits.
ALOE BARBADENSIS
Nourishing, Hydrating
Enriched with elements like vitamins C and E, this ingredient complements the skin's natural moisture barrier, contributing to a feeling of smoothness and protection.
HOW TO USE
Twice Daily
Apply Matrixyl® 3000 Collagen Serum to improve appearance of fine lines and wrinkles.
As seen in
What's included
· Matrixyl® 3000 Collagen Boosting Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml
PEPTIDE SERUM
PEPTIDE COMPLEX 10% WRINKLE DEFENSE SERUM
★★★★★ [600+ Reviews]
✓ Improves the appearance of wrinkles by 7.22% | ✓ Skin feels smoother and softer
[USE TWICE DAILY]
A powerful line defense serum formulated with Argireline™ peptide, clinically proven to improve the appearance of wrinkles and support moisture for smoother-looking, replenished skin.
About Argireline™ peptide
Argireline™ peptide is a trademark of Lubrizol Advanced Materials, Inc.
KEY INGREDIENTS
ARGIRELINE™ 10%
Wrinkle Reducing
Targets dynamic wrinkles, aiming to reduce wrinkle depth and length, resulting in smoother and more youthful-looking skin.
VITA-POLYPEPTIDE
Radiant Boosting
An advanced, stable form of Vitamin C, derived from the combination of ascorbic acid and a polypeptide. It provides anti-aging benefits and protects the skin from free radicals.
K-SCIENCE BLEND
Calming
A blend of beloved K-beauty natural extracts, including Cica, Heartleaf, Fig Extract, and Camomile Flower oil, which offer protective and soothing benefits for your skin.
VITAMIN E
Moisturizing
A potent antioxidant, Vitamin E protects the skin from free radicals and combats premature aging. It also aids in moisturization by creating a barrier to retain moisture and improve hydration.
HOW TO USE
Twice Daily
Targeted application of Peptide Complex 10% Wrinkle Defense Serum on problem areas.
As seen in
What's included
· Matrixyl® 3000 Collagen Boosting Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml