Depology Peptide-Serum Duo

$80 $89

[PEPTIDE DUO - USE DAY AND NIGHT]

Depology’s Peptide Serum Duo includes two signature serums that blend potent peptides with effective ingredients to reduce the appearance of both static and dynamic wrinkles, enhancing a youthful and hydrated glow.

PRODUCT INFORMATION

Peptide Complex 10% Wrinkle Defense Serum

A potent serum formulated with Argireline™ peptide, known for its ability to support a more relaxed look of facial expressions, effectively improving the appearance of dynamic lines.

Matrixyl® 3000 Collagen Serum

A supercharged serum containing 5% Matrixyl® 3000, designed to minimize the look of deep static wrinkles and support a collagen-rich skin appearance.

Disclaimer ↓

The Content, statements, and other material made available on or through the Site: (i) are not intended to diagnose, treat, cure, or prevent any medical condition or disease; and (ii) are not in any way intended as medical advice or as a substitute for medical treatment.

BENEFITS & WHY CHOOSE

  • Minimizes the appearance of both static and dynamic wrinkles
  • Delivers hydration for a plump, smooth appearance
  • Helps protect the skin from environmental stressors
  • Suitable for all skin types, including sensitive skin

Depology Peptide Serum Duo is designed to offer an integrated solution that single products cannot match.

Each serum effectively works on different types of wrinkles on its own. When used together, they enhance each other’s benefits, resulting in more noticeable and long-lasting improvements in skin texture and overall appearance.

HOW TO USE

Step [1]

Cleanse and tone skin to prepare for treatment.

Step [2]

Apply Peptide Complex 10% Serum

Apply Peptide Complex 10% Serum to areas with dynamic wrinkles, such as crow's feet and forehead lines. Wait until fully absorbed.

Step [3]

Follow with Matrixyl® 3000 Collagen Serum

Follow with Matrixyl® 3000 Collagen Serum, applying it all over the face, including the neck area.

Shipping policy

We ship worldwide. We provide customers from the USA and International postal tracking via email.

Paraben Free

Gluten Free

Synthetic Fragrance Free

Synthetic Color Free

· ​Matrixyl® 3000 Collagen Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml

· Matrixyl® 3000 Collagen Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml

Only 31800 pieces in stock!

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Shipping policy

We ship worldwide. We provide customers from the USA and International postal tracking via email.

Paraben Free

Gluten Free

Synthetic Fragrance Free

Synthetic Color Free

IN THIS DUO SET

ORIGINAL VALUE - $89.00

Bundle Price - $80.00

Targets

Dynamic lines

Elasticity loss

Suited For

Dull and dry skin

Benefits

- Reduces dynamic wrinkle appearance

- Improves skin texture

- Enhances skin moisture

Disclaimer ↓

About Argireline™ peptide:

Argireline™ peptide is a trademark of Lubrizol Advanced Materials, Inc.​

Targets

Static lines

Firmness loss

Suited For

Sensitive and dehydrated skin

Benefits

- Reduces static wrinkle appearance

- Supports a more youthful appearance

- Contributes to a healthy glow

Disclaimer ↓

About Matrixyl® 3000:

Matrixyl® 3000 is a trademark of Sederma Inc and neither Depology Holdings nor Depology Skincare is affiliated with Sederma Inc.​

SEE THE TRANSFORMATION FROM OUR REAL CUSTOMERS!

"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."

@beauty**

"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."

@beauty**

"For the first time in a long time I love what I see in the mirror!! I’m 49 years old and was looking tired. Now no one believes I’m in my late 40s, everyone thinks I’m in my 30s. Can’t believe how quickly I saw results."

@@robiny**

SEE THE TRANSFORMATION FROM OUR REAL CUSTOMERS!

"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."

@beauty**

"This is my result after using the Depology Peptide Serum Duo. Increased hydration, my fine lines are minimized and face is plump and glowy. Loving this combo."

@beauty**

For the first time in a long time I love what I see in the mirror!! I’m 49 years old and was looking tired. Now no one believes I’m in my late 40s, everyone thinks I’m in my 30s. Can’t believe how quickly I saw results.

@robiny**

[1] DYNAMIC WRINKLES

Dynamic wrinkles are caused by repetitive facial movements such as smiling, frowning, or squinting. These wrinkles typically appear in areas with frequent muscle activity and are most commonly seen as:

- Frown lines
- Forehead lines
- Crow's feet

[1] DYNAMIC WRINKLES

Dynamic wrinkles are caused by repetitive facial movements such as smiling, frowning, or squinting. These wrinkles typically appear in areas with frequent muscle activity and are most commonly seen as:

- Frown lines
- Forehead lines
- Crow's feet

Argireline™ peptide

Argireline™ peptide is a powerful ingredient known for its ability to target dynamic wrinkles. It can help to relax the appearance of expression lines and smoothing the skin.

[2] STATIC WRINKLES

Static wrinkles are the result of the natural aging process, including the loss of skin elasticity and collagen over time. These wrinkles are present even when the face is at rest and typically appear as

- Smile lines
- Cheek lines
- Marionette lines

[2] STATIC WRINKLES

Static wrinkles are the result of the natural aging process, including the loss of skin elasticity and collagen over time. These wrinkles are present even when the face is at rest and typically appear as

- Smile lines
- Cheek lines
- Marionette lines

Matrixyl® 3000 Peptide

Matrixyl® 3000 is a renowned peptide complex known for its ability to promote a smoother look and improve skin texture, contributing to a firmer appearance. This advanced formula helps reduce the visible signs of aging, providing a more youthful and revitalized complexion.

[1] DYNAMIC WRINKLES

Dynamic wrinkles are caused by repetitive facial movements such as smiling, frowning, or squinting. These wrinkles typically appear in areas with frequent muscle activity and are most commonly seen as:

- Frown lines
- Forehead lines
- Crow's feet

Argireline™ peptide

Argireline™ peptide is a powerful ingredient known for its ability to target dynamic wrinkles. It can help to relax the appearance of expression lines and smoothing the skin.

[2] STATIC WRINKLES

Static wrinkles are the result of the natural aging process, including the loss of skin elasticity and collagen over time. These wrinkles are present even when the face is at rest and typically appear as

- Smile lines
- Cheek lines
- Marionette lines

Matrixyl® 3000 Peptide

Matrixyl® 3000 is a renowned peptide complex known for its ability to promote a smoother look and improve skin texture, contributing to a firmer appearance. This advanced formula helps reduce the visible signs of aging, providing a more youthful and revitalized complexion.

RECOMMENDED BY SKINCARE PROFESSIONALS

Dr. Anthony Youn

Board-certified plastic surgeon

“They are both premium Korean peptide serums known for their science-backed formulas and luxurious feel on the skin.”

Dr. Laura Soong

Board Certified Dermatologist

“I highly recommend you give this wrinkle best combination a try!”

Dr. Sanya Kundra

Medical Cosmetologist

“The serum is lightweight, absorbs quickly, and leaves my skin feeling incredibly hydrated and smooth. My skin feels firmer and looks more radiant—exactly what I was hoping for!”

Dr. Taewoon Kim

Board-certified plastic surgeon

"I first used these two Depology products two years ago, and I noticed an improvement in the appearance of the wrinkles in my under-eye area.”

CLINICAL TRIAL RESULTS AFTER JUST 4 WEEKS OF USE

Wrinkle index decreased by

7.22%

Wrinkle index decreased by

7.22%

Skin hydration increased by

46.31%

Skin hydration increased by

46.31%

HOW TO USE

Step [1]

Thoroughly cleanse and tone the skin.

Step [2]

Argireline Serum [Peptide Complex 10% Serum]

Apply 3-4 drops of serum onto your palm and gently massage it onto the face, focusing on dynamic wrinkle areas such as: Frown lines, Forehead lines and Crow's feet.

Step [3]

Matrixyl 3000 Serum

Let the Argireline Serum absorb for 1-2 minutes. Then apply 3-4 drops of Matrixyl 3000 serum onto your palm and gently massage it onto the face, focusing on static wrinkle areas such as: Smile lines, Cheek lines and Marionette lines.

Step [4]

Let the Matrixyl 3000 Serum absorb and follow up with your favorite moisturizer.

RECOMMENDED BY SKINCARE PROFESSIONALS

Dr. Anthony Youn

Board-certified plastic surgeon

“They are both premium Korean peptide serums known for their science-backed formulas and luxurious feel on the skin.”

Dr. Laura Soong

Board Certified Dermatologist

“I highly recommend you give this wrinkle best combination a try!”                                                                                      

Dr. Sanya Kundra

Medical Cosmetologist

“The serum is lightweight, absorbs quickly, and leaves my skin feeling incredibly hydrated and smooth. My skin feels firmer and looks more radiant—exactly what I was hoping for!”

Dr. Taewoon Kim

Board-certified plastic surgeon

"I first used these two Depology products two years ago, and I noticed an improvement in the appearance of the wrinkles in my under-eye area.”                                                                

HOW TO USE

Step [1]

Thoroughly cleanse and tone the skin.

Step [2]

Argireline Serum [Peptide Complex 10% Serum]

Apply 3-4 drops of serum onto your palm and gently massage it onto the face, focusing on dynamic wrinkle areas such as: Frown lines, Forehead lines and Crow's feet.

Step [3]

Matrixyl 3000 Serum

Let the Argireline Serum absorb for 1-2 minutes. Then apply 3-4 drops of Matrixyl 3000 serum onto your palm and gently massage it onto the face, focusing on static wrinkle areas such as: Smile lines, Cheek lines and Marionette lines.

Step [4]

Let the Matrixyl 3000 Serum absorb and follow up with your favorite moisturizer.

CUSTOMER TESTIMONIALS

Highly recommend!

“I live in a city with very dry climate. This peptide combo gives me the moisture my skin needs. The caviar stick is also great. I carry it and use it when i need that extra moisture. My skin has improved since using Depology products. Highly recommend! ”

- TBUI

Verified Buyer

My skin has never been so healthy and smooth.

“Since using my Depology serums and products I have gotten so many compliments and questions as to what I use . My skin has never been so healthy and smooth you can see a big difference in texture along with minimal wrinkles . People ask me how at 70 do I manage to look younger ! I’ve recommended Depology to my family too! ”

- Henry Cruz

Verified Buyer

My skin looking the best it ever has!

“The combination of these products has my skin looking the best it ever has! My skin stays looking hydrated and plump throughout the entire day!”

- Linda Mitchell

Verified Buyer

I love the way it feels on my skin.

“I have been using Peptide Serum Duo for about a month. I love the way it feels on my skin and I am seeing better skin texture and suppleness.”

- Tracy

Verified Buyer

I love this serum.

“I love this serum. I keep getting compliments on how dewy and healthy it looks. I am 48 years old and I have not taken great care of my skin until recently. This serum is changing the texture, tone, and it feels soft to touch.”

- Lawreen

Verified Buyer

CUSTOMER TESTIMONIALS

Highly recommend!

“I live in a city with very dry climate. This peptide combo gives me the moisture my skin needs. The caviar stick is also great. I carry it and use it when i need that extra moisture. My skin has improved since using Depology products. Highly recommend! ”

- TBUI

Verified Buyer

My skin has never been so healthy and smooth

“Since using my Depology serums and products I have gotten so many compliments and questions as to what I use . My skin has never been so healthy and smooth you can see a big difference in texture along with minimal wrinkles . People ask me how at 70 do I manage to look younger ! I’ve recommended Depology to my family too! ”

- Henry Cruz

Verified Buyer

My skin looking the best it ever has!

“The combination of these products has my skin looking the best it ever has! My skin stays looking hydrated and plump throughout the entire day!”

- Linda Mitchell

Verified Buyer

I love the way it feels on my skin

“I have been using Peptide Serum Duo for about a month. I love the way it feels on my skin and I am seeing better skin texture and suppleness. ”

- Tracy

Verified Buyer

I love this serum.

“I love this serum. I keep getting compliments on how dewy and healthy it looks. I am 48 years old and I have not taken great care of my skin until recently. This serum is changing the texture, tone, and it feels soft to touch.”

- Lawreen

Verified Buyer

FAQ

Can I use one serum that includes both Matrixyl® 3000 and Argireline™ peptide?

No, we recommend using the serums separately for optimal results. Apply Peptide Complex 10% Argireline™ Peptide Serum first and wait until it is fully absorbed before applying Matrixyl® 3000 Collagen Serum. This method ensures each ingredient works effectively on its targeted wrinkles.

Can these serums be paired with Retinol or Retinoids?

Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum can be used with retinol. They complement each other well, enhancing the overall benefits for your skin.

Should I use these serums on damp or dry skin?

For best results, apply the serums on damp skin. This helps with better absorption and maximizes the effectiveness of the active ingredients.

How often do I need to use these serums?

Both serums can be used daily, preferably twice a day—morning and night—for best results. Consistency is key to seeing noticeable improvements in skin texture and appearance.

Are these serums suitable for all skin types?

Yes, both Peptide Complex 10% Argireline™ Peptide Serum and Matrixyl® 3000 Collagen Serum are suitable for all skin types. They are formulated to be gentle yet effective, providing anti-aging benefits without irritation.

COLLAGEN SERUM

MATRIXYL® 3000 COLLAGEN SERUM

★★★★★ [3000+ Reviews]
✓ Improves hydration by 46.31% | ✓ Makes the skin plump and glowy

[USE TWICE DAILY]

A supercharged plumping serum formulated with Matrixyl® 3000, designed to help reduce the appearance of aging signs and promote a youthful, hydrated glow.

About Matrixyl®

Matrixyl® is a trademark of Sederma Inc and neither Depology Holdings nor Depology Skincare is affiliated with Sederma Inc.

KEY INGREDIENTS

MATRIXYL 3000


Rejuvenating

Our core ingredient, formed from two peptides that work synergistically to restore and maintain the skin’s youthful characteristics.

HYALURONIC ACID


Hydrating

Our core ingredient, aids in the binding of water to collagen, retaining it in the skin for a plumper, and more hydrated appearance.

COLLAGEN


Plumping, Nourishing

This innovative collagen extract from yeast is synergistic with natural collagen, visibly diminishing signs of aging and delivering moisturizing benefits.

ALOE BARBADENSIS


Nourishing, Hydrating

Enriched with elements like vitamins C and E, this ingredient complements the skin's natural moisture barrier, contributing to a feeling of smoothness and protection.

HOW TO USE

Twice Daily

Apply Matrixyl® 3000 Collagen Serum to improve appearance of fine lines and wrinkles.

As seen in

What's included

· Matrixyl® 3000 Collagen Boosting Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml

PEPTIDE SERUM

PEPTIDE COMPLEX 10% WRINKLE DEFENSE SERUM

★★★★★ [600+ Reviews]
✓ Improves the appearance of wrinkles by 7.22% | ✓ Skin feels smoother and softer
 

[USE TWICE DAILY]

A powerful line defense serum formulated with Argireline™ peptide, clinically proven to improve the appearance of wrinkles and support moisture for smoother-looking, replenished skin.

About Argireline™ peptide

Argireline™ peptide is a trademark of Lubrizol Advanced Materials, Inc.

KEY INGREDIENTS

ARGIRELINE™ 10%


Wrinkle Reducing

Targets dynamic wrinkles, aiming to reduce wrinkle depth and length, resulting in smoother and more youthful-looking skin.

VITA-POLYPEPTIDE


Radiant Boosting

An advanced, stable form of Vitamin C, derived from the combination of ascorbic acid and a polypeptide. It provides anti-aging benefits and protects the skin from free radicals.

K-SCIENCE BLEND


Calming

A blend of beloved K-beauty natural extracts, including Cica, Heartleaf, Fig Extract, and Camomile Flower oil, which offer protective and soothing benefits for your skin.​

VITAMIN E


Moisturizing

A potent antioxidant, Vitamin E protects the skin from free radicals and combats premature aging. It also aids in moisturization by creating a barrier to retain moisture and improve hydration.​

HOW TO USE

Twice Daily

Targeted application of Peptide Complex 10% Wrinkle Defense Serum on problem areas.

As seen in

What's included

· Matrixyl® 3000 Collagen Boosting Serum - 30ml
· Peptide Complex 10% Wrinkle Defense Serum - 30ml

Customer Reviews

Based on 776 reviews
86%
(664)
7%
(51)
2%
(16)
1%
(6)
5%
(39)
S
Sam
Peptide Serum Duo

The best product. Can't complain

J
Jessie Devine
Great serum!

I'm almost finished with my first bottle and will definitely be reordering! Skin is bright, smooth, and overall feels great!

L
Lourdes Soto
Peptide Serum Duo

My skin looks smoother and glowy. I love this wonderful combination.

A
Alisha
Wrinkle free

This stuff is magic! My wrinkles have drastically improved.

J
Jessica Salenga
Peptide Serum Duo

Amazing I really love it! Show the result. Saved money for the duo.